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IRBs must develop SOPs for ensuring prompt reporting of which of the following?

  1. Financial conflicts of interest

  2. Changes in research activity

  3. Publication of results

  4. All meetings and discussions

The correct answer is: Changes in research activity

An IRB must develop SOPs for ensuring prompt reporting of changes in research activity. This is because changes in research activity can impact the safety and well-being of research participants and may require additional ethical review. Financial conflicts of interest (A) do not necessarily require prompt reporting, as long as they are properly managed and disclosed. Publication of results (C) and all meetings and discussions (D) are not under the jurisdiction of an IRB, and thus do not require SOPs for reporting.