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What method is primarily used for QA during a trial?

  1. Automated data analysis

  2. Study monitor visitations

  3. Clinical site's internal reviews

  4. Participant surveys

The correct answer is: Clinical site's internal reviews

The primary method used for Quality Assurance (QA) during a trial is the clinical site's internal reviews. This is because the clinical site is responsible for conducting the trial and ensuring that all processes and procedures are being followed correctly. Automated data analysis (Option A) may be used as a tool for QA, but it is not the primary method as it cannot replace the human oversight and judgment of clinical site personnel. Study monitor visitations (Option B) may also be used for QA, but it is not the central method as it only involves periodic check-ins and does not provide a continuous review of the trial processes. Participant surveys (Option D) may be implemented for QA purposes, but they are typically used for collecting feedback and evaluating the trial experience, rather than directly assessing the trial procedures.