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When is expedited review by an IRB appropriate?

  1. When the study involves more than minimal risk

  2. For all studies involving children

  3. If the study involves no more than minimal risk

  4. Only for initial review of the study

The correct answer is: If the study involves no more than minimal risk

An expedited review by an IRB is appropriate when the study involves minimal risk to participants. This means that the study poses little to no harm or discomfort to the participants. Option A is incorrect because an expedited review may not be necessary if the study poses more than minimal risk. Option B is incorrect because expedited review is not solely based on the involvement of children, but rather on the level of risk in the study. Option D is incorrect because expedited review can be used for both initial and continuing review of a study.